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Job Details

Argonne National Laboratory

Computational Biologist




Full Time


Lemont, Illinois, United States

We are seeking an experienced bioinformatician to join our team that develops and maintains a large web-based analysis resource for the infectious disease research community. This resource, known as the Bacterial and Viral Bioinformatics Resource Center (BV-BRC), is funded by the NIH/NIAID. The BV-BRC provides integrated genomic data analysis and visualization tools to the biomedical research community focusing on infectious diseases, including bacteria and viruses. This position is located at Argonne National Laboratory with a joint appointment at the University of Chicago.

The successful candidate applies bioinformatics and machine learning techniques to research problems in the life sciences with an emphasis on using computational approaches for detecting sequence patterns in a variety of contexts including complex microbial community (metagenomic) datasets. The successful candidate also develops and applies computational models on new experimental data, provides measures of uncertainty, and participates in interdisciplinary discussions aimed at the design of new experiments. Problems typically involve the construction of computational models for phenotype and/or class prediction from genomic sequence data and other genomics data. The successful candidate will report on results of research including publishing scholarly papers in scientific journals, giving presentations at conferences, meetings, and seminars, and participates in the preparation of reports and proposals required by funding agencies to obtain and continue funding support.

Position Requirements

  • Master’s and 3+ years of experience, or PhD and 0+ years of experience in bioinformatics, computational biology, computer science, or biology, or equivalent
  • Knowledge of machine learning and/or statistics
  • Knowledge of bioinformatics analysis techniques and tools
  • Experience with NGS data analysis workflows
  • Understanding of computational algorithms to support DNA sequence alignment, small nucleotide polymorphism detection
  • Experience with bacterial genomics and metagenomics (demonstrated work in microbiology preferred)
  • Fluency in Perl or Python preferred
  • Familiarity with the Unix command line environment and commands
  • Analytical and problem-solving skills required
  • Ability to think independently and innovatively to develop exceptional technical solutions required
  • Effective verbal and written communication skills
  • Ability to write research reports and publications
  • Organizational skills and attention to detail
  • Ability to work independently and as part of a team
  • Collaborative skills, including the ability to interact well with external collaborators preferred
  • Ability to model Argonne’s Core Values: Impact, Safety, Respect, Integrity, and Teamwork

Job Family

Research Development (RD)

Job Profile

Software Engineering 2

Worker Type


Time Type

Full time

As an equal employment opportunity and affirmative action employer, and in accordance with our core values of impact, safety, respect, integrity and teamwork, Argonne National Laboratory is committed to a diverse and inclusive workplace that fosters collaborative scientific discovery and innovation. In support of this commitment, Argonne encourages minorities, women, veterans and individuals with disabilities to apply for employment. Argonne considers all qualified applicants for employment without regard to age, ancestry, citizenship status, color, disability, gender, gender identity, gender expression, genetic information, marital status, national origin, pregnancy, race, religion, sexual orientation, veteran status or any other characteristic protected by law.

Argonne employees, and certain guest researchers and contractors, are subject to particular restrictions related to participation in Foreign Government Sponsored or Affiliated Activities, as defined and detailed in United States Department of Energy Order 486.1A. You will be asked to disclose any such participation in the application phase for review by Argonne's Legal Department.

All Argonne offers of employment are contingent upon a background check that includes an assessment of criminal conviction history conducted on an individualized and case-by-case basis. Please be advised that Argonne positions require upon hire (or may require in the future) for the individual be to obtain a government access authorization that involves additional background check requirements. Failure to obtain or maintain such government access authorization could result in the withdrawal of a job offer or future termination of employment.

Please note that all Argonne employees are required to be vaccinated against COVID-19. All successful applicants will be required to provide their COVID-19 vaccination verification as a condition of employment, subject to limited legally recognized exemptions to COVID-19 vaccination.