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Job Details


Abbott

Principal Scientist - R&D Antibody Development (31021233)

Pharmaceuticals

All

Yearly

Full Time

No

Pomona, California, United States

Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 113,000 colleagues serve people in more than 160 countries.

About Abbott

Diagnostic testing is a compass, providing information that helps in the prevention, diagnosis and treatment of a range of health conditions.

Abbott’s life-changing tests and diagnostic tools give you accurate, timely information to better manage your health. We’re empowering smarter medical and economic decision making to help transform the way people manage their health at all stages of life. Every day, more than 10 million tests are run on Abbott’s diagnostics instruments, providing lab results for millions of people.

Our location in Pomona, CA currently has an opportunity for a Principal Scientist within our Rapid Diagnostics Division Toxicology Business Unit. As a competent scientist, you will plan and conduct work requiring specialized techniques in selecting and evaluating approaches to problems, and ability to apply an analytical approach to the solution of a variety of problems, and to assimilate the details and significance of various scientific analyses, procedures and tests.

WHAT YOU’LL DO

  • Research and development of antibodies by using leading edge technologies

  • Construction of high quality of rFab library in an efficient way

  • Supervising junior level scientists

  • Initiate new research and experiments, lead projects or multiple smaller projects, develop and execute more advanced preclinical scientific research and/or development.

  • Use professional concepts to contribute to the development of company concepts and principles and to achieve objectives in creative and effective ways.

  • Independent researcher, seeks advice for most complex/challenging work, likely participates in development of patent applications.

  • May determine methods and procedures on new assignments and provides guidance to junior personnel.

  • Provide sound and original suggestions for new problems.

  • Plan and conduct work requiring specialist techniques in selecting and evaluating approaches to problems, and ability to apply an analytical approach to the solution of a variety of problems, and to assimilate the details and significance of various scientific analyses, procedures and tests.

  • Work in marginally complex problems in which analysis of situations or data requires an in-depth evaluation of various factors.

  • Must be proficient in Design Control process

  • Design experiments based on deliverables and plan activities to meet the project timelines

  • Conduct complex experimentation including data collection, summary and thorough analysis, in support of department research projects and guidelines. Compose robust experimentation strategies that maximize effective use of resources and time to deliver optimum information.

  • Perform analytical test methods on the finished products based on CLSI and other FDA guidelines

  • Participate as an integral member of the scientific staff in research strategy and methodology to resolve issues

  • Provide recommendations and observations to scientific staff and management on results of projects/tasks. Play a key role in the research strategies and tactics for new or existing R&D projects.

  • May lead small project teams and direct day to day work of less experienced employees.

  • May be involved in interviewing, training employees, planning, assigning, directing work and resolving technical problems.

  • Write clinical trial protocol and order materials needed to complete procedures; documents development work, writing technical reports and cost estimates.

  • Submits ideas for inventions; publishes, innovates through patent filings and/or scientific publications. Capable of performing FTO’s (Freedom to Operate).

  • Able to provide direction to project team to meet economic profitability (EP) profile for the project (product cost analysis).

  • Innovate research methods and product formulation to resolve problems and accomplish company objectives. Pro-actively recommend strategy to overcome hurdles.

  • Maintain records of laboratory activities and notebooks in a professional, accurate manner. May provide support to regulatory and intellectual property activities.

  • Transfer developed processes to the Manufacturing Team. Write and revise process document reports and transfer protocols.

  • Ability to create, review, and work with SOPs, MPs, and Batch Records

  • Operate complex laboratory equipment and perform routine maintenance and repair. Interface with contracted repair technicians as required. Understand theoretical basis for analytical instrumentation.

  • May functionally direct junior research staff, as required.

  • Initiate literature review and searches to support ongoing research activities. Summarize findings in final form to management and recommend follow-up actions.

  • Generate oral and written reports and to summarize laboratory activities and projects per R&D manger’s request. Initiate communication with R&D manager and functions as necessary to coordinate other staffs’ activities effectively.

  • Monitor and maintain necessary laboratory supplies, with approval by senior department staff or R&D manager

  • Work involving urine, blood or other potentially infectious materials may be required

  • Knowledgeable of federal and other regulations, e.g. QSR’s, ISO, ISO 13485, CMDR

  • Understands and is aware of the quality consequences which may occur from the improper performance of their specific job; has awareness of device defects that may occur in their area of responsibility, including product design, verification and validation, manufacturing and testing activities

  • Responsible for exhibiting professional behavior with both internal/external business associates that reflects positively on the company and is consistent with the company’s policies and practices; build productive internal/external working relationships

  • Carries out duties in compliance with established business policies

  • Other duties as assigned, according to the changing needs of the business

EDUCATION AND EXPERIENCE YOU’LL BRING

Required

  • PhD in biologics with extensive experience in developing commercial antibodies

  • Demonstrated track record of novel antibody development through rFab technology

  • 7+ years pf progressively responsible positions in a research development environment.

  • Experience with multiple immunoassay platforms and technologies

  • Ability to functionally direct and train junior research staff

  • Ability to work well with global teams, including time-zone flexibility

  • Excellent presentation, oral and written communication skills, computer skills with MS Word, Excel, PowerPoint, JMP, and other statistical programs

  • Operate complex laboratory equipment and perform routine maintenance

  • Ability to communicate and work with external and internal Abbott Rapid Diagnostic development partners, resource planning and management of time across multiple projects


Preferred

  • Strong experience in Design Control process

  • Hands-on experience developing assays to semi-quantitative or qualitative drug levels, anti-drug antibodies, and pharmacodynamic measures of activity using immunoassays and/or other methodologies

  • Experience interpreting and reporting complex immunogenicity data

  • Experience in Quality Assurance, i.e. CAPA, quality incidents

  • Process orientated, logical, analytical, meticulous, highly organized and able to analyze data and implement solutions

WHAT WE OFFER

At Abbott, you can have a good job that can grow into a great career. We offer:

  • A fast-paced work environment where your safety is our priority

  • Production areas that are clean, well-lit and temperature-controlled

  • Training and career development, with onboarding programs for new employees and tuition assistance

  • Financial security through competitive compensation, incentives and retirement plans

  • Health care and well-being programs including medical, dental, vision, wellness and occupational health programs

  • Paid time off

  • 401(k) retirement savings with a generous company match

  • The stability of a company with a record of strong financial performance and history of being actively involved in local communities

Learn more about our benefits that add real value to your life to help you live fully: [Register to View]

Follow your career aspirations to Abbott for diverse opportunities with a company that provides the growth and strength to build your future. Abbott is an Equal Opportunity Employer, committed to employee diversity.

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