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Job Details

Bristol-Meyers Squibb, Co.

Principal Scientist - Genetic Toxicology (R1557666-en-us)





New Brunswick, New Jersey, United States

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Position Summary

Bristol-Myers Squibb (BMS) is seeking a Principal Scientist to join the Genetic and Occupational Toxicology group in the department of Nonclinical Safety to manage genetic toxicology studies and assist in development of testing strategies in support of drug candidate selection and regulatory submissions. This individual will be responsible for determining genotoxic modes of action, assessing genotoxic risk, and assessing and implementing new laboratory methods.

Key Responsibilities

  • Lead genetic toxicology lab activities including monitoring out-sourced studies, and acting as study director/contributing scientist for in-house studies (GLP and exploratory)

  • Ensure studies conducted for regulatory submission comply with applicable regulatory guidance and OECD test guidelines

  • Provide genetic toxicology subject matter expertise to drug development teams for de-risking discovery candidates and assist with formulation of de-risking strategies

  • Lead and contribute as a bench scientist to assessment and implementation of new emerging technologies

  • Assist with impurity hazard assessment and development of control limits

  • Maintain current understanding of new developments and trends in the field of genetic toxicology and potential implications to drug development

Qualifications & Experience

  • PhD in Toxicology or related field with at least 3-5 years of appropriate post-doctoral experience or MS with equivalent scientific background in genetic toxicology, DNA damage/repair, or chemical mutagenesis/carcinogenesis.

  • Advanced understanding of international test guidelines

  • Clear communication of genotoxicity test results/strategy and scientific concepts

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to . Visit[Register to View] target="_blank"> [Register to View] to access our complete Equal Employment Opportunity statement.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.