Antibody Discovery Scientist
The Biologics Center (NBC) is accommodated within the Novartis Institutes for BioMedical Research (NIBR). NBC, in collaboration with the disease areas and technical expert groups, builds the future biologics therapy pipeline of Novartis through the discovery and creation of new antibody, protein, nucleic acid and virus-based molecules.
We are looking for a Senior Scientist who is highly motivated, flexible and an adaptable team player to join the Antibody Discovery group within NBC in Cambridge, MA. You will participate in the generation of high-quality biologics to initiate and competitively advance the NIBR biologics pipeline by independently performing antibody screening followed by binding and functional characterization.
Your responsibilities include, but are not limited to:
•Apply state-of-the art immunization-based antibody discovery techniques with the associated, B-cell isolation, hybridoma generation, selection, cell culture and high-throughput screening.
•Perform antibody sequencing from hybridoma and/or single B-cells.
•Characterize antibody properties through various techniques for affinity and activity.
•Work effectively and collaboratively in a large team within function as well as across functions.
•Independently generate hypotheses, troubleshoot, design, and execute experiments with the input from senior team members, mentors and supervisors.
•Document experimental results contemporaneously and comprehensively in laboratory notebooks as well as in internal Databases.
•Present research updates and participate constructively in working project teams and at laboratory group meetings.