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Bristol-Meyers Squibb, Co.

Principal Scientist, Translational Early Program Lead (R1559690-en-us-3)

Pharmaceuticals

All

Yearly

No

Summit, New Jersey, United States

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology, and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

The Immunology, Cardiovascular, Fibrosis, and Global Health (ICFG) Thematic Research Center (TRC) at BMS is one of the fundamental Research and Early Development (R&ED) units delivering therapeutics to patients. Our mission is to create transformative medicines of tomorrow based on the cutting-edge science of today. We leverage BMS’s internal invention of engine that includes industry-leading expertise in small molecule chemistry, protein biotherapeutics, cell therapy, protein degradation, nucleic acids, and other therapeutic modalities. We work closely our R&ED colleagues in clinical and non-clinical development, project leadership, translational medicine, and informatics to advance therapies based on a deep understand of causal human biology. Further, we collaborate across the biopharmaceutical ecosystem to establish partnerships that complement our internal expertise.

The Translational Early Program Lead will be part of the Immunology, Cardiovascular, and Fibrosis (ICF) Thematic Research Center (TRC). Working in a cross functional team, the individual will be responsible for the development of the clinical biomarker strategy for early-stage drug development programs. This individual will also have matrixed responsibilities to guide research programs within the translational research laboratories and will act as the translational development ICF TRC representative in early development teams and assume primary responsibilities, such as interacting with CROs and KOLs to support contracting, sample analysis, and data delivery and interpretation of biomarkers in clinical studies. The ideal candidate could either have prior translational experience or have experience in another relevant domain of therapeutical development. First and foremost we seek a candidate with a passion to learn and interact with various functions across an organization to deliver science that accelerates the development of medicines for patients in need.

Key Responsibilities

  • Responsible for managing the timelines and activities associated with clinical biomarker data delivery such as biomarker and assay selection, contracting (with support from an operations group), sample analysis, interpretation, and report generation, as well as involvement in trial-specific biomarker deliverables (e.g. biomarker plan, protocol development, study reports).
  • Work with internal translational research groups or CROs to develop and validate and selected biomarker assays for clinical implementation.
  • Implement innovative translational activities in early clinical studies through direct interaction with clinical research physicians, statisticians, clinical operations, computational biologists, contract research organizations, academic experts, and internal translational scientists.
  • Acts as a liaison between scientific and clinical project representatives to bridge the gap between discovery/translational research and clinical early development and enable back-translation from clinical studies to bench scientists.
  • Aid in biomarker data delivery for clinical studies through working with relevant functions and CROs; supports development of SOWs and interfacing with CRO for execution of services
  • Participate in evaluation of CROs for data analysis and delivery capabilities, as needed
  • Identify and collaborate in disease or therapeutic area-specific academic/industry partnerships and consortia, with the goal of advancing scientific understanding of disease pathophysiology to enable early target and biomarker identification and validation
  • Prepare and deliver internal and external presentations
  • Support regulatory submissions and regulatory interactions as needed

Qualifications & Experience

  • A Ph.D. with 5+ years or a BS with 10+ years of relevant experience in biotechnology / pharmaceutical industry and/or other relevant experience is required. The candidate must be a rigorous, detail-oriented scientist, with excellent record keeping and organizational skills. The candidate must also be a highly flexible, results oriented, independent self-starter who enjoys working in a fast-paced dynamic environment.
  • Experience in some of the following area will be prioritized
    • Basic knowledge of either immunology, cardiovascular or fibrosis
    • A basic understanding of drug discovery and development, with a focus on transitioning from a preclinical to a clinical stage of development
    • Activities required for and related to clinical trial initiation, maintenance, and completion
    • Global regulatory interactions
    • Interacting with CROs and KOLs managing interactions
    • Proven scientific and/or leadership expertise working in teams, mentoring and/or managing projects
    • Mining of large datasets, either independently or in collaboration with bioinformaticians
    • Excellent record of performance and scientific accomplishments as demonstrated by impactful contributions to the scientific community, pipeline contributions, peer reviewed publications and patent applications desired
    • Excellent verbal and written communication skills

Why You Should Apply

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to . Visit[Register to View] target="_blank"> [Register to View] to access our complete Equal Employment Opportunity statement.

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