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Job Details

GlaxoSmithKline (GSK)

Senior Director Complex In Vitro Models



Full Time

On Site


Collegeville, Pennsylvania, United States

Site Name: USA - Pennsylvania - Upper Providence, UK - Hertfordshire - Stevenage
Posted Date: Jul 14 2022

This position will consider candidates from the UK and US that meet the minimum qualifications.

As a Senior Director Complex In Vitro Models you will be responsible to deliver an integrated enterprise strategy for sustained, portfolio driven growth in R&D by application of complex human-relevant and translatable complex in vitro models including Microphysiological Systems (MPS) and Organoids.

This role will lead the implementation and evolution of biologically relevant in vitro technologies and deliver a strong impact at GSK through increased adoption, impact (attrition reduction), and modernization. Key influencer in the external environment through connections with external experts/opinion leaders. Drives coordination and prioritization of activities.

Key Responsibilities:

This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following.

- Lead, manage and mentor an agile team of scientists to drives efficient & well prioritized discovery, characterization, development and clinical success of safe and effective medicines through application of appropriate complex biologic models, with a focus on complex in vitro models
- Develop team members for greater enterprise and translational thinking, to emphasize focus on defining the biological question(s)
- Advocate a culture of scientific challenge and peer review of existing models and of new technological opportunities. Proactively collaborate with preclinical and clinical scientists across the organization to increase the translational value of GSK pre-clinical decision-making and, ultimately leading to attrition reduction.
- Ensures organizational and platform integration to enable a continuous evolution of capability, aligned with the needs of the portfolio
- Create an environment that supports open communication, inspires creative innovation and encourages the team to exceed their own expectations
-Provide a centralized core of support for the development, application and continued innovation of complex in vitro models

- Leads the CIVM technology strategy across R&D by identifying and leveraging external innovators, undertaking business due diligence, and leading the development of external alliances along with technology evaluation and transfer into GSK to meet the needs of the R&D portfolio.

- Understands the R&D portfolio needs, develops relationships with stakeholders that support the uptake and operation of CIVMs by Research Units and other functional lines.

- Develops multi-year strategic business plans for CIVM technology assessment and acquisition

- Facilitates scientific exchange across lines among the CIVM community of users

Raise awareness and provide expert advice and recommendations on complex in vitro platforms based on scientific merit, practicality and potential impact on drug development at GSK
- Lead complex in vitro model team to drive scientific and technological exchange between internal and external partners to ensure smooth transfer of capabilities, when capabilities have reached an appropriate state of maturity relative to performance criteria and desired characteristics
-Ensure the team’s engagement and collaboration with existing capabilities throughout GSK dedicated to bringing awareness of novel complex in vitro cell culture technologies to GSK stakeholders.
- Leverage resource from within the GSK scientific community through networking and maximize the use of the complex in vitro cell culture database to focus efforts on where more complex in vitro models are required
- Coordinate the complex in vitro model matrix to leverage existing internal expert knowledge and skills, and raise awareness of novel complex in vitro model platforms, as well as influence Research Unit’s commitment to CIVM development, validation and implementation
-Engage scientists in pro-active scientific dialogue to build inter-disciplinary bridges and a pre-clinical to clinical line of sight across GSK and external partners
- Provide high quality scientific and strategic guidance which impact model development, validation, relevance, conduct, analysis, and reporting

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

  • PhD in Cellular Biology/Molecular Biology or an equivalent life sciences degree

  • 10 years of biomedical or pharmaceutical or academic research and application of CIVM, MPS, organoids.

  • Experience leading a group responsible for delivering tactical and operational management of multi-site research programs with Complex In Vitro Models

  • Track record of competency in leadership skills, critical thinking, proactive operational excellence, and strategic planning with the ability to build networks and manage by influence across a diverse and inclusive customer and stakeholder base

  • Strong change management skills

  • Strong customer focus and ability to influence across the enterprise

  • Establishes baseline; compares with benchmarks; establishes strategy that meets business needs for operational metrics to meet business needs for the portfolio

  • Ability to coach, mentor, develop, execute comprehensive talent management and performance manage staff through accountability

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

  • 15 years of biopharmaceutical experience in drug discovery and development

  • Develops and maintains internal and external networks of technical experts to draw upon for expertise, advice, and service including having a strong external profile and being viewed externally as a key opinion leader

  • Executive presence capability regarding communications to senior management on functional line contributions and impact on the portfolio

  • Ability to work routinely across boundaries and establish cross functional matrix collaborations and teams

Why GSK?

At GSK, we have already delivered unprecedented change over the past four years, improving R&D, becoming a leader in Consumer Health, strengthening our leadership, and transforming our commercial execution. Now, we’re making the biggest changes we’ve made to our business in over 20 years. We’re on track to separate and create two new companies in 2022: New GSK with a leading portfolio of vaccines and specialty medicines as well as R&D based on immune system and genetics science; and a new world-leading consumer healthcare company of loved and trusted brands.​

With new ambition comes new purpose. For New GSK, this is to unite science, talent and technology to get ahead of disease together – all with the clear ambition of delivering human health impact; stronger and more sustainable shareholder returns; and as a new GSK where outstanding people thrive.​

Getting ahead means preventing disease as well as treating it. How we do all this is through our people and our culture. A culture that is ambitious for patients – so we deliver what matters better and faster; accountable for impact – with clear ownership of goals and support to succeed; and where we do the right thing. So, if you’re ready to improve the lives of billions, join us at this exciting moment in our journey. Join our challenge to get Ahead Together.​


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