Job was saved successfully.
Job was removed from Saved Jobs.

Job Details

Bristol-Meyers Squibb, Co.

Director, Translational Research Oncology



Full Time

On Site


Brisbane, California, United States

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

The Oncogenesis Thematic Research Center at BMS is one of the fundamental research and early development engines delivering oncology therapeutics to patients. The Oncogenesis TRC has a major focus of exploiting BMS’ expertise in protein degradation to discover and develop therapies aimed at tumor intrinsic vulnerabilities and mechanisms of resistance to existing cancer therapeutics. This focus on protein degradation allows us to attack protein classes that were previously deemed undruggable. The group integrates discovery research through translational and early clinical development and exploits state-of-the-art in vitro, in vivo and ex-vivo models of cancer biology to identify and validate targets and partners closely with colleagues in Translational Development, Informatics and Predictive Sciences and Early Clinical Development to generate biomarker and patient enrichment hypotheses to enable efficient decision making in early clinical trials.

Position Responsibilities

In the role as a Director within the Oncogenesis Translational Team, the ideal candidate:

  • Has real-world experience with the translational aspects of clinical trials, and a track record of designing, executing, and interpreting translational data to provide insight and support program decisions

  • Can serve as subject matter expert for health authority interactions

  • Provides scientific leadership and management on cross-site and cross-functional teams

  • Leads group of translational scientists whose activities span cell-based, in vivo, and clinical trial assays, samples, and data

  • Manage (directly and via direct and indirect reports) the selection, validation, and deployment of novel clinical-stage assay methods and analysis of data to accelerate development and provide insight into disease biology and drug mechanisms

  • Design and interpret experiments to define dose-schedules, patient selection markers and other biomarker readouts, combination strategies and pathways of drug resistance for oncology programs

  • Design and oversee execution of experiments to test hypotheses from clinical observations in preclinical model systems

  • Present key data at governance committees, internal forums, and external meetings

  • Author and oversee writing of study reports, patents, and peer-reviewed publications. Presentation of methods, results and conclusions to publishable standards

  • Lead the identification, planning and execution of collaborative projects with leading academic and commercial research groups worldwide.

  • Management and hiring responsibility for translational scientists including direct and indirect reports up to the Sr. Principal Scientist/ Associate Director level.

  • Supervise contract research organizations to achieve high standards of productivity and quality.

  • Manage projects to successful outcomes through scientific leadership, teamwork and influence, and direct reporting relationships

  • Mentor research staff through instruction, coaching, and guidance

  • Work across geographies and scientific domains


Basic Qualifications:

  • Bachelor’s Degree

    • 15+ years of academic and / or industry experience


  • Master’s Degree

    • 12+ years of academic and / or industry experience


  • Ph.D. or equivalent advanced degree in the Life Sciences

    • 8+ years of academic and / or industry experience

  • 6+ years of leadership experience

Preferred Qualifications:

  • Ph.D., or scientific experience and development equivalent to a Ph.D., with 12+ years of post-Ph.D. experience including 6+ years of drug discovery and development experience in an industry setting

  • Recognized expert in clinical translational studies including sampling, analysis, and interpretation of multiple data types

  • Strategic leader able to define program priorities, resources, and strategies

  • Experienced and successful manager able to build and motivate teams, define goals and objectives, provide guidance and mentorship, negotiate conflicts, and optimize deployment of team resources to achieve objectives

  • Comprehensive knowledge of cancer biology and drug development

  • Proven ability to derive novel insights from complex data

  • Ability to interpret and summarize scientific data in an accurate, critical and concise manner

  • Strong understanding, derived from direct participation, of the design and execution of clinical trials incorporating translational science and correlative endpoints

  • Expertise in biomarker discovery and development, with advanced skills in assay design, development, validation, and troubleshooting

  • Experienced in the integration of preclinical research through to clinical drug development

  • Highly effective teamwork and interpersonal skills

  • Exceptional written and verbal communications skills.

  • Functional group advisor/go-to person.

  • Able to assess risk & develop contingency plans.

  • Serves as subject matter expert and functional group advisor on science, technology, methods, etc.


Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to . Visit[Register to View] target="_blank"> [Register to View] to access our complete Equal Employment Opportunity statement.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.