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Job Details

Merck & Co. Inc.

Senior Scientist



Full Time

On Site


West Point, Pennsylvania, United States

Job Description

Our Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to isolate a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities and robust scientific methodology, we collaborate to discover the next medical breakthrough.

The Vaccine Analytical Research & Development department of our Research & Development Division is seeking applicants for a Senior Scientist position available at its West Point, Pennsylvania research facility. The Senior Scientist is a laboratory-based scientific role tasked with solving complex analytical problems at the interface of biology, chemistry, and lab informatics disciplines to enable development of Vaccine supporting process development, formulation development, vaccine investigations and method lifecycle management.

In this role, an individual will work with a team of scientists to develop state-of-the-art analytical techniques, such as separations of small molecules, polymers, proteins, conjugates, and nanoparticles (Akta FPLC, HPLC and CE), spectroscopic techniques (UV-VIS / IR / Fluorescence), Immunoassay, and classical chemistry techniques. The individual should also have in-depth knowledge of analytical techniques, molecular structure characterization to facilitate vaccine development. Lab automation / informatics is considered a plus.

The successful candidate must function well and be able to collaborate in a fast-paced, integrated, multidisciplinary team environment. Applicants must have effective organizational, multi-tasking, oral/written communications skills, show scientific leadership, and a desire to conduct research and publish. Experience leading small groups of technical personnel and analytical projects will aid in distinguishing candidates. Evidence of strong cross-functional collaboration in an academic or industrial setting is also preferred.

Education Minimum Requirements:

  • Ph.D. degree in analytical chemistry, chemistry, biochemistry, biomedical engineering or related field or M.S. degree with a minimum of 4 years of experience in the Biotech/Pharmaceutical Industry, or B.S. degree with a minimum of 7 years of experience in Biotech/Pharmaceutical Industry.

Required Experience and Skills:

  • In-depth knowledge and understanding of separation science (HPLC, CE, LC-MS, SDS-PAGE, & WB) demonstrated by publications.

  • Extensive experience with UPLC/HPLC analysis of biologics or vaccines (e.g. SEC, RP, IEX) and CE techniques.

  • A strong team player with excellent oral and written communication skills; ability to work both independently for development of assays and cross-functionally.

  • Demonstrated scientific ability through publications and presentations in scientific conferences.

Preferred Experience and Skills:

  • Experience with qualification, validation, and transfer of assays to a GLP or regulated laboratory environment as listed in ICH Q2 and USP<1033>..

  • Experience in representing analytical functional area on project teams.

  • Authoring and reviewing internal technical reports, sections of regulatory filings (e.g. IND, BLA) and external scientific publications.

  • Strong ability to deliver complex objectives under aggressive timelines in a rapidly changing environment.

  • Ability to design, execute and/or direct development and qualification of release, characterization and stability assays for testing of clinical trial material and in support of product and process development.

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” and that great medicines can make a significant impact to our world. And we believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

Who we are …

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for …

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization.


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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

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Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

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Travel Requirements:

No Travel Required

Flexible Work Arrangements:


Not Indicated

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Requisition ID:R129880