Senior Scientist, Biology-Discovery (R131926)
We’re seeking an innovative, highly motivated, and experienced Senior Scientist to join the Infectious Disease and Vaccines department at our research site in West Point, PA.
The candidate will be responsible for conceiving, designing, and implementing experiments to advance the development of mRNA based vaccines and therapeutics in the areas of Infectious Disease. This will require collaboration with cross-functional teams including colleagues in Systems Biology, Discovery Chemistry, Bioprocess and Information Technology, The candidate should have a strong background in RNA Biology (e.g., structure, function, immunology), and cutting-edge methodologies related to vaccine design. The candidate will be expected to independently design, execute, and analyze experiments and should have a strong background in immunological techniques.
The candidate must demonstrate well-developed skills for effective communication of scientific information and should have a strong history of publication in peer-reviewed journals. We value creative-thinking, teamwork, and independent analytical problem solving. If you are a highly motivated team player with a strong desire to impact basic research and translational medicine, we invite you to consider joining our team.
Responsibilities include but are not limited to:
mRNA design, production and evaluation in vitro and in vivo
Data interpretation and presentation, manuscript/patent preparation
PhD with >1 year postdoctoral experience
Competency in multiple aspects of RNA biology and nucleic acid sequence analysis (e.g., structure, stability, function, expression, immunogenicity, regulation and engineering).
Proven track record in molecular techniques, including molecular cloning, cell culture, protein expression, purification and characterization
Proficient in biochemical and immunological assays (ELISA, SPR, WB, FACS, etc.)
Independent experimental design and execution, analytical problem-solving capabilities
Excellent written and oral communication skills, and demonstrate the ability to work collaboratively in a matrix team environment
Demonstrated record of publication in peer-reviewed scientific journals
Approximately 10% Travel.
Knowledgeable of drug/vaccine discovery and experience in translational research
Experience in virology, bacteriology and animal models is desirable
Awareness of machine learning approaches (deep learning, neural networks, tree-based algorithms, and support vector machines) with application to predicting features and behavior of mRNA molecules.
Exposure to concepts in Information Technology (e.g., knowledge management, ML operations, data capture, databases, and biopolymer registration).
We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.
Who we are …
We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.
What we look for …
Imagine getting up in the morning for a job as important as helping to save and improve lives around the world. Here, you have that opportunity. You can put your empathy, creativity, digital mastery, or scientific genius to work in collaboration with a diverse group of colleagues who pursue and bring hope to countless people who are battling some of the most challenging diseases of our time. Our team is constantly evolving, so if you are among the intellectually curious, join us—and start making your impact today.
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